Table 2

Sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) at optimal points in the receiver operating characteristic (ROC) curve (maximum sum of sensitivity and specificity) for the various reperfusion markers

Probability of reperfusion (q) Sensitivity (%) Specificity (%) PPV (%) NPV (%)
First hour increase rate of:
FABP (μg/l/h)0.6671698744
Myoglobin (μg/l/h)0.6767718842
CK-MB (U/l/h)0.7352758734
QHBDH72 plus first hour increase rate of:
FABP (μg/l/h)0.7874939755
Myoglobin (μg/l/h)0.7873899552
CK-MB (U/l/h)0.7577718950
  • CK-MB, creatine kinase MB isoenzyme; FABP, fatty acid binding protein; QHBDH72, cumulative release of α hydroxybutyrate dehydrogenase in the first 72 hours.