Haemodynamic performance during ischaemia-reperfusion protocol
| Group | Stabilisation period | 5 min ischaemia | 30 min ischaemia | 5 min reperfusion | 120 min reperfusion |
| Heart rate (beats/min) | |||||
| Sham + V | 283 (6) | 281 (11) | 276 (15) | 281 (15) | 281 (12) |
| Sham + Che | 290 (11) | 272 (17) | 270 (16) | 268 (26) | 286 (17) |
| Ex + V | 298 (9) | 286 (8) | 301 (9) | 286 (13) | 254 (31) |
| Ex + Che | 276 (4) | 264 (10) | 276 (11) | 267 (8) | 264 (6) |
| Left ventricular developed pressure(mm Hg) | |||||
| Sham + V | 119 (8) | 66 (9) | 85 (7) | 86 (8) | 81 (8) |
| Sham + Che | 120 (6) | 55 (4) | 75 (5) | 99 (7) | 88 (4) |
| Ex + V | 105 (4) | 58 (7) | 73 (6) | 91 (6) | 82 (5) |
| Ex + Che | 101 (8) | 47 (4) | 73 (3) | 104 (6) | 80 (4) |
| Rate–pressure product (mm Hg/min × 1000) | |||||
| Sham + V | 33.9 (2.8) | 18.9 (2.9) | 23.5 (2.3) | 24.9 (3.3) | 23.1 (2.7) |
| Sham + Che | 31.9 (2.6) | 14.6 (1.1) | 20.7 (1.5) | 25.5 (2.4) | 24.9 (1.5) |
| Ex + V | 31.4 (1.7) | 16.4 (1.9) | 22.0 (1.9) | 25.9 (2.0) | 21.3 (3.1) |
| Ex + Che | 30.4 (2.0) | 14.9 (0.7) | 18.8 (1.5) | 28.4 (1.9) | 20.9 (1.2) |
Values are mean (SD).
Ex + Che, chelerythrine treated before exercise; Ex + V, vehicle treated before exercise; Sham + Che, chelerythrine treated before sham procedure; Sham + V, vehicle treated before sham procedure.