Table 2

Correlation between individual systolic and diastolic variables, clinical severity of heart symptoms, and plasma adrenomedullin concentrations

	All patients		Systolic heart failure with RFP		Systolic heart failure with non-RFP		Diastolic heart failure
Variable	r	p Value	r	p Value	r	p Value	r	p Value
E velocity	0.25	< 0.05	0.52	< 0.005	0.04	NS	0.003	NS
A velocity	−0.13	NS	−0.02	NS	0.03	NS	0.32	NS
E:A ratio	0.33	0.005	0.35	< 0.05	0.07	NS	−0.22	NS
Deceleration time of E	−0.13	NS	0.19	NS	−0.02	NS	0.43	< 0.05
Isovolumic relaxation time	0.01	NS	−0.02	NS	0.27	NS	−0.10	NS
End diastolic dimension	0.25	< 0.05	0.10	NS	0.18	NS	0.21	NS
End systolic dimension	0.21	NS	0.09	NS	0.20	NS	0.18	NS
Fractional shortening	−0.17	NS	−0.02	NS	−0.21	NS	0.04	NS
LVEF by M mode	−0.20	NS	−0.11	NS	−0.23	NS	0.04	NS
LVEF by Simpson's method	−0.15	NS	−0.06	NS	−0.10	NS	−0.19	NS
Left atrial size	0.18	NS	0.26	NS	0.03	NS	0.02	NS
PASP	0.03	NS	−0.22	NS	−0.05	NS	0.13	NS
NHYA class	0.14	NS	0.21	NS	0.29	NS	0.27	NS
Diuretics used	0.12	NS	0.30	NS	−0.16	NS	−0.28	NS

A velocity, transmitral peak atrial filling velocity; E velocity, transmitral peak early filling velocity; E:A ratio, ratio of transmitral early to atrial peak filling velocity; LVEF, left ventricular ejection fraction; NYHA, New York Heart Association; PASP, pulmonary arterial systolic pressure; RFP, restrictive filling pattern of diastolic dysfunction.