Reactivity of coronary stenoses and their reference segments to intracoronary administration of L-arginine (L-A) and nitrates
| Morphology | Minimum lumen diameter (mm) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Stenoses | Reference segments | |||||||||
| Baseline | LA-50 | LA-150 | Nitrates | Baseline | LA-50 | LA-150 | Nitrates | |||
| Smooth (n=12) | 1.66 (0.08) | 1.76 (0.12) | 1.80 (0.14) | 1.89 (0.13) | 2.92 (0.16) | 3.05 (0.18) | 3.23 (0.23) | 3.28 (0.20) | ||
| +6.4 (1.4)% | +7.3 (2.9)% | +14.9 (3.4)% | +4.5 (1.4)% | +10.5 (1.4)% | +12.3 (3.5)% | |||||
| Complex (n=10) | 1.32 (0.17) | 1.42 (0.20) | 1.52 (0.20) | 1.60 (0.20) | 2.84 (0.20) | 3.04 (0.20) | 3.10 (0.20) | 3.23 (0.18) | ||
| +7.1 (3.2)% | +13.7 (2.5)%2-150 | +19.4 (2.3)% | +6.3 (2.9)% | +10.4 (2.4)% | +10.4 (2.5)% | |||||
Values are mean (SEM).
↵2-150 p < 0.05 v smooth stenoses.
LA-50, 50 μmol L-arginine/min; LA-150, 150 μmol L-arginine/min.