Septal long axis response to dobutamine stress
| Variable | Controls (n=20) | Normal LV cavity (n=25) | Dilated LV cavity and restrictive filling | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| QRS < 120 ms | QRS > 120 ms | |||||||||||||
| Rest | Stress | Rest | Stress | Rest | Stress | Rest | Stress | |||||||
| Total long axis amplitude (cm) | 1.4 (0.3) | 1.7 (0.2)3-165 | 1.1 (0.3)3-151 | 1.1 (0.3) | 0.8 (0.3)3-161 | 0.7 (0.3) | 0.3 (0.2) 3-153 | 0.4 (0.3) | ||||||
| Long axis shortening during ejection (%) | 85 (3) | 91 (6)3-165 | 75 (8)3-164 | 62 (13)3-165 | 61 (14)3-171 | 42 (16)3-165 | 46 (13)3-153 | 34 (12)3-160 | ||||||
| Shortening velocity (cm/s) | 6.9 (1.6) | 11.3 (1.7)3-165 | 4.8 (1.9)3-164 | 7.9 (3.2)3-160 | 2.6 (0.8)3-171 | 4.6 (2.4)3-160 | 1.1 (1.2)3-153 | 2.5 (2.4)3-150 | ||||||
| Lengthening velocity (cm/s) | 6.1 (1.7) | 8.2 (2.4)3-165 | 4.2 (2.7)3-164 | 4.6 (2.9) | 2.2 (1.1)3-152 | 2.9 (1.8) | 0.1 (1.8)3-153 | 0.7 (2.4) | ||||||
| Postejection shortening (mm) | 0 | 0 | 0.7 (0.9)3-164 | 1.9 (1.4)3-165 | 0.8 (1.2) | 1.8 (1.8)3-160 | 1.0 (1.2) | 1.3 (1.5) | ||||||
Values are mean (SD).
↵3-150 p < 0.01,
↵3-160 p < 0.005,
↵3-165 p < 0.001 stress versus rest within group (paired t test);
↵3-151 p < 0.01,
↵3-164 p < 0.001 rest value normal cavity size versus rest value control (unpaired ttest);
↵3-152 p < 0.01,
↵3-161 p < 0.005,
↵3-171 p < 0.001 rest value DCM-NA versus rest value normal cavity (unpairedt test);
↵3-153 p < 0.005 rest value DCM-LBBB versus rest value DCM-NA (unpaired t test).