Cardiac transplantation indication criteria
| ICD, implantable cardioverter-defibrillator; NYHA, New York Heart Association; Vo2, oxygen consumption. | |
| 1. Accepted | Heart Failure Survival Score (HFSS, Aaronson 19976) high risk |
| Peak Vo2 <10 ml/kg/min after reaching anaerobic threshold | |
| NYHA class III/IV heart failure refractory to maximal medical treatment | |
| Severely limiting ischaemia not amenable to interventional or surgical revascularisation | |
| Recurrent symptomatic ventricular arrhythmias refractory to medical, ICD, and surgical treatment | |
| 2. Probable | HFSS medium risk |
| Peak Vo2 <14 ml/kg/min and severe functional limitations | |
| Instability of fluid status and renal function despite good compliance, daily weights, salt and fluid restriction and flexible diuretics | |
| Recurrent unstable ischaemia not amenable to revascularisation | |
| 3. Inadequate | HFSS low risk alone |
| Peak Vo2 >15–18 ml/kg/min without other indications | |
| Left ventricular ejection fraction <20 % alone | |
| History of NYHA class III/IV symptoms alone | |
| History of ventricular arrhythmias alone | |