Table 1

Changes in echocardiographic measurements during preload altering manoeuvres

VariableBaselineStage 1Stage 2Stage 3
Values are mean (SD).
p Values: stages 1–3 v baseline: *p=0.001; †p=0.003; ‡p=0.01; §p=NS (p>0.05).
Stage 1, Trendelenberg manoeuvre; stage 2, reverse Trendelenberg manoeuvre; stage 3, amyl nitrate inhalation.
E, left ventricular early mitral inflow velocity; EDTV, early diastolic velocity; LVEDV, left ventricular end diastolic volume.
LVEDV (ml)*198.6 (132.2)242.2 (186.2)212.1 (163.0)188.1 (132.9)
Left atrial area (mm2)†22.4 (8.6)23.9 (10.0)21.7 (9.6)20.1 (7.7)
E wave (cm/s)‡82.4 (33.1)84.6 (32.2)71.9 (25.9)72.8 (20.2)
EDTV (cm/s)§10.3 (3.5)10.7 (3.1)10.7 (3.4)11.1 (3.7)
Systolic blood pressure (mm Hg)*126.4 (18.6)122.9 (16.9)118.1 (21.0)103.2 (21.5)