Comparison of SF-36 scales in heart failure patients in different functional classes, and between heart failure patients, patients with other diseases, and the general population
| CHF patients | Comparison groups | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| NYHA class | |||||||||
| SF-36 scales | Ia (n=24) | IIb (n=98) | IIIc (n=83) | Totald (n=205) | Dialysis (n=120) | Hepatitis (n=70) | Major depression (n=502) | Normal (n=906) | |
| Significance (a,b,c,d ): p<0.05 by t tests between groups with the designated letters and NYHA I (a), NYHA II (b), NYHA III (c), and entire heart failure population (d). To control for the multiplicity problem of multiple comparisons, only adjusted p values are reported (after Bonferoni <0.00156). | |||||||||
| CHF, congestive heart failure; NYHA, New York Heart Association. | |||||||||
| Physical functioning | Mean | 79.2 | 56.7 | 29.2 | 48.3 | 50.7 | 79.3 | 71.6 | 96.6 |
| SD | 20.4 | 21.3 | 20.0 | 26.9 | 30.8 | 23.3 | 27.2 | 10.0 | |
| Significance | b,c | a,c | a,b | a,c | b,c,d | b,c,d | a,b,c,d | ||
| Role-physical | Mean | 60.4 | 28.9 | 10.7 | 25.5 | 28.6 | 56.9 | 44.4 | 96.9 |
| SD | 41.6 | 37.4 | 26.9 | 37.5 | 37.2 | 43.5 | 40.3 | 13.9 | |
| Significance | b,c | a,c | a,b | a,c | b,c,d | b,c,d | a,b,c,d | ||
| Bodily pain | Mean | 85.9 | 65.7 | 52.7 | 63.1 | 63.7 | 72.6 | 58.8 | 94.6 |
| SD | 20.2 | 28.9 | 33.1 | 31.5 | 27.3 | 27.4 | 26.7 | 15.0 | |
| Significance | b,c | a,c | a,b | a | c | a | b,c,d | ||
| General health | Mean | 63.8 | 44.5 | 31.7 | 41.7 | 43.0 | 52.7 | 52.9 | 79.9 |
| SD | 17.1 | 17.1 | 15.0 | 19.2 | 20.2 | 25.7 | 23.0 | 13.7 | |
| Significance | b,c | a,c | a,b | a,c | c,d | b,c,d | a,b,c,d | ||
| Vitality | Mean | 61.2 | 49.5 | 29.3 | 42.8 | 48.9 | 48.3 | 40.1 | 71.9 |
| SD | 19.0 | 19.6 | 17.0 | 21.9 | 24.0 | 24.2 | 21.1 | 14.3 | |
| Significance | c | c | a,b | c | a,c | a,b,c | a,b,c,d | ||
| Social functioning | Mean | 80.7 | 75.4 | 57.2 | 68.5 | 63.1 | 65.5 | 57.2 | 94.9 |
| SD | 19.8 | 23.9 | 27.4 | 26.9 | 29.6 | 26.2 | 27.7 | 12.3 | |
| Significance | c | c | a,b | a,b | a | a,b,d | b,c,d | ||
| Role-emotional | Mean | 76.4 | 55.0 | 32.9 | 49.1 | 52.5 | 59.5 | 38.9 | 96.9 |
| SD | 38.7 | 45.7 | 43.7 | 46.3 | 45.4 | 41.0 | 39.8 | 14.3 | |
| Significance | c | c | a,b | a,c | c | a,b | b,c,d | ||
| Mental health | Mean | 74.0 | 66.3 | 51.4 | 61.2 | 63.3 | 59.4 | 46.3 | 79.2 |
| SD | 19.3 | 17.9 | 20.4 | 20.8 | 20.5 | 22.1 | 20.8 | 13.1 | |
| Significance | c | c | a,b | c | a | a,b,d | b,c,d | ||