Cross sectional and Doppler echocardiographic findings in hypertrophic cardiomyopathy and controls
| Variable | HCM | Control | p Value |
|---|---|---|---|
| Values are mean (SD). | |||
| A, late left ventricular filling velocity; E, early left ventricular filling velocity; HCM, hypertrophic cardiomyopathy; IVS, interventricular septum; LA, left atrial; LV, left ventricular. | |||
| Cross sectional echocardiography | |||
| LV dimensions | |||
| End diastole (mm) | 42 (5) | 45 (4) | <0.001 |
| End systole (mm) | 23 (5) | 27 (4) | <0.0001 |
| Fractional shortening (%) | 46 (8) | 41 (5) | <0.0001 |
| Thickness | |||
| IVS (mm) | 18 (5) | 9 (1) | <0.0001 |
| Posterior wall (mm) | 11 (3) | 9 (1) | <0.0001 |
| LA dimension (mm) | 42 (6) | 33 (5) | <0.0001 |
| Doppler echocardiography | |||
| LV filling flow | |||
| Transmitral E (cm/s) | 71 (21) | 75 (15) | NS |
| Transmitral A (cm/s) | 55 (23) | 49 (13) | NS |
| E/A ratio | 1.5 (0.7) | 1.6 (0.6) | NS |
| E deceleration time (ms) | 215 (69) | 145 (30) | <0.0001 |
| Isovolumic relaxation time (ms) | 90 (19) | 72 (12) | <0.0001 |
| Pulmonary venous flow | |||
| Peak systolic velocity (cm/s) | 56 (14) | 50 (11) | <0.05 |
| Peak diastolic velocity (cm/s) | 43 (10) | 51 (14) | <0.01 |
| Peak atrial systolic velocity (cm/s) | 30 (10) | 21 (6) | <0.0001 |