Table 3

Comparison of levels of risk factors and inflammatory markers by CagA status in case and control groups

Case groupControl group
CagA positive (n=105)CagA negative (n=96)p ValueCagA positive (n=176)CagA negative (n=238)p Value
For quantitative variables mean (SD) is given. CRP, C reactive protein; BMI, body mass index; DBP, diastolic blood pressure; MCDS, mean Carstairs deprivation score; SBP, systolic blood pressure; WCC, white cell count. *Further education refers to proportion of subjects who studied beyond school level; †employment refers to proportion of subjects in employment at start of study; ‡although mean data are shown, analysis was done on log CRP, as the distribution of values was skewed.
Age (years)57.6 (5.1)56.1 (5.4)0.03957.2 (5.1)56.6 (5.5) 0.203
Smokers (%)51.551.00.95657.947.9 0.043
BMI (kg/m2)26.0 (3.2)25.5 (2.9)0.21725.7 (2.8)25.8 (3.1) 0.716
LDL cholesterol (mmol/l)5.0 (0.4)5.0 (0.4)0.9985.0 (0.4)4.9 (0.4) 0.461
HDL cholesterol (mmol/l)1.1 (0.2)1.1 (0.3)0.1401.1 (0.2)1.1 (0.2) 0.452
SBP (mm Hg)139 (18)142 (19)0.359137 (17)137 (17) 0.671
DBP (mm Hg)86 (10)87 (12)0.25484 (11)84 (11) 0.873
Diabetes (%)0.03.10.0681.11.3 0.905
Hypertension (%)27.622.90.44415.914.4 0.660
MCDS1.34 (3.48)0.40 (3.50)0.0601.55 (3.72)0.33 (3.50)<0.001
Further education (%)*16.128.10.04113.124.9 0.003
Employment (%)†60.064.60.50459.765.8 0.199
WCC (× 10−3/mm3)7.0 (2.0)7.0 (2.1)0.9476.9 (1.9)6.6 (1.8) 0.141
Fibrinogen (g/l)4.4 (0.8)4.5 (1.0)0.3474.4 (1.1)4.4 (0.9) 0.581
CRP (mg/l)‡4.1 (4.9)4.6 (6.6)0.5673.7 (7.7)3.2 (5.3)0.715