Elsevier

American Heart Journal

Volume 106, Issue 2, August 1983, Pages 292-299
American Heart Journal

Arrhythmias and left ventricular function after defibrillation during acute myocardial infarction in the intact dog

https://doi.org/10.1016/0002-8703(83)90195-3Get rights and content

Abstract

The purpose of this study was to assess the recovery of the left ventricular pressure (PLV), and the incidence and type of arrhythmias after effective low-dose defibrillation (Imax = 18 − 70 A) in healthy hearts and in hearts with acute myocardial infarction (AMI) in the intact dog. In fifteen dogs 84 episodes of fibrillation-defibrillation were studied in the healthy heart and 53 episodes were studied in the acute phase of myocardial infarction 12 to 3 hours after occlusion of a part of the left anterior descending artery by a catheter technique. Time to recovery of PLV depended on duration of fibrillation (tF) and cumulative defibrillation current (I12), and became critical at tF > 45 seconds and I12 > 45 A. Total duration of arrhythmias due to defibrillation increased with increasing tF and I12. Arrhythmias which have a relative greater chance of resulting in refibrillation or which may seriously decrease the cardiac output occurred more often with I12 > 55 A (p < 0.001), when 50% of episodes were followed by these arrhythmias. No differences were found in responses between the healthy heart and the heart with AMI.

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