Amiodarone for refractory atrial fibrillation
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Cited by (195)
Atrial Structure and Function and its Implications for Current and Emerging Treatments for Atrial Fibrillation
2015, Progress in Cardiovascular DiseasesCitation Excerpt :Older studies had suggested that in the setting of amiodarone therapy, LA dimensions may not significantly predict AF outcomes. However, these studies may have preferentially selected patients prone to recurrence, and assessments of LA dimensions at that stage (with primarily M-mode echocardiography) were likely crude at best.116 Apart from predicting AF, LA diameter has been independently associated with ischaemic stroke in women, and increased all cause mortality in all patients, including those without AF, although whether this represents an independent risk factor or merely non-diagnosed subclinical AF remains unclear.117
Comparison of the effects of bepridil and aprindine for the prevention of atrial fibrillation after cardiac and aortic surgery: A prospective randomized study
2015, Journal of ArrhythmiaCitation Excerpt :It is thus probable that the rapid pharmacological efficacy of bepridil influenced the results of the present study. The predictors of AF recurrence and chronicity after anti-arrhythmic treatment for maintaining sinus rhythm reportedly include the duration of AF [33], AF history [34], left atrial dimension [35], underlying cardiac disease [36], aging [37], and development of the mixed type [38]. In this prospective randomized study, these factors did not differ significantly between the bepridil and aprindine groups.
Pharmacology of Antiarrhythmic Drugs in Elderly Patients
2012, Clinics in Geriatric MedicineCitation Excerpt :Amiodarone is also the most effective drug for treating refractory atrial fibrillation in terms of converting atrial fibrillation to sinus rhythm. However, because of the high incidence of adverse effects caused by amiodarone, it should be used in low doses in patients with atrial fibrillation when life-threatening atrial fibrillation is refractory to other therapy.50 Sotalol is a nonselective β-blocker with class III antiarrhythmic activity.
Current strategies of antiarrhythmic drug therapy for paroxysmal atrial fibrillation
2012, Journal of ArrhythmiaCitation Excerpt :It is likely that the wide variability in the percentage of patients successfully treated with antiarrhythmic drugs was caused by differences in patient profiles among the studies. It has been suggested that recurrence of AF is associated with aging [19,20], duration of AF episodes [21,21], AF history [23], increased left atrial dimension [21,22,24], the presence of underlying heart disease (e.g., valvular and ischemic heart diseases) [21,25], and circadian variation in AF onset (mixed AF type) [26], among other factors. Moreover, patients in Western countries receive different types of antiarrhythmic drugs at doses 1.5- to 2-fold higher than the standard doses in Japan.
2011 ACCF/AHA/HRS Focused Updates Incorporated Into the ACC/AHA/ESC 2006 Guidelines for the Management of Patients With Atrial Fibrillation: A Report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines Developed in partnership with the European Society of Cardiology and in collaboration with the European Heart Rhythm Association and the Heart Rhythm Society
2011, Journal of the American College of CardiologyCardiac Arrhythmias
2010, Brocklehurst's Textbook of Geriatric Medicine and Gerontology