Effect of intracoronary injections of sonicated microbubbles on left ventricular contractility☆
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Interleukin 8 targeted contrast echocardiography is effective to evaluate myocardial ischemia-reperfusion injury in the rabbits
2019, Biomedicine and PharmacotherapyCitation Excerpt :Moreover, IL-8 level increased in patients who undergo cardiopulmonary bypass and PTCA [18,19]. With the development of ultrasound contrast agents and imaging techniques, myocardial blood flow could be measured quantitatively by myocardial contrast echocardiography (MCE) [20–22]. A large European multicenter study showed that SonoVue-enhanced MCE had superior sensitivity but a lower specificity for detection of coronary artery disease (CAD) compared to SPECT [23].
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2007, Current Problems in CardiologyCitation Excerpt :To improve the safety profile, reproducibility, and clinical feasibility, attention was turned towards the development of stable microbubbles that are able to pass freely through pulmonary and systemic capillaries that are typically 5 to 7 μm in diameter.8,9 High-energy sonication of dextrose solutions or iodinated radiopaque contrast agents improved the size distribution somewhat but these agents were to unstable for intravenous use and tended to affect hemodynamics.10-13 The advent of encapsulated microbubble contrast agents has solved many of the problems with stability and size optimization.
3D perfusion mapping in post-infarct mice using myocardial contrast echocardiography
2006, Ultrasound in Medicine and BiologyMyocardial contrast echocardiography: Basic principles
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This work was supported in part by grants from the Goldblatt Research Foundation and the Amoco Foundation, Chicago, Illinois.