Effect of iron deficiency on tissue oxygen delivery in cyanotic congenital heart disease☆
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Cited by (15)
Hematologic Manifestations of Childhood Illness
2018, Hematology: Basic Principles and PracticeHematologic Manifestations of Childhood Illness
2017, Hematology: Basic Principles and PracticeSeeking optimal relation between oxygen saturation and hemoglobin concentration in adults with cyanosis from congenital heart disease
2011, American Journal of CardiologyCitation Excerpt :A linear relation has been shown, although less steep than ours.5,7,8 A right shift of the oxyhemoglobin dissociation curve has been seen in iron-deficient children.9 We also previously reported a less steep relation in iron-replete adults with patients with Eisenmenger syndrome.6
Cyanotic Congenital Heart Disease: A Multisystem Disorder
2008, Congenital Heart Disease in AdultsBlood Viscosity and its Relationship to Iron Deficiency, Symptoms, and Exercise Capacity in Adults With Cyanotic Congenital Heart Disease
2006, Journal of the American College of CardiologyCitation Excerpt :Phlebotomy-induced iron deficiency has been shown to lower fibrinogen levels in select patients (25), lending further support to our finding that iron deficiency actually decreases RBC aggregation. We found a significant right-shifted oxygen-Hb dissociation curve in iron-deficient patients, which is consistent with some (26) but not all studies (17). The rightward shift favors tissue oxygen release in response to decreased systemic oxygen transport.
Hematological management of the cyanotic adult with congenital heart disease
2004, International Journal of Cardiology
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This study was supported in part by the Robert and Mary Wood Research Fellowship Grant.