F-18 deoxyglucose and stress N-13 ammonia positron emission tomography in anterior wall healed myocardial infarction

doi:10.1016/0002-9149(88)91153-8

The American Journal of Cardiology

Volume 61, Issue 15, 1 June 1988, Pages 1191-1197

https://doi.org/10.1016/0002-9149(88)91153-8 Get rights and content

Abstract

To evaluate myocardial blood flow and glucose utilization, N-13 ammonia (NH₃) and F-18 deoxyglucose positron emission tomography scanning was performed in 22 patients with previous anterior wall myocardial infarction, using a high-resolution, multi-slice, whole-body scanner. The N-13 ammonia study was performed at rest and after exercise. The F-18 deoxyglucose study was performed at rest after fasting >5 hours. The N-13 ammonia study revealed a hypoperfused area in 19 of the 22 patients (86%), that corresponded to the infarcted regions as diagnosed by electrocardiography, coronary arteriography and left ventriculography (21 patients). The hypoperfused areas expanded after exercise in 16 of 22 patients (73%). F-18 deoxyglucose uptake was observed in these hypoperfused areas, especially in patients with hypokinetic wall motion on left ventriculography and in exercise-induced hypoperfused areas. However, positron emission tomography demonstrated diffuse uptake of F-18 deoxyglucose in 3 of 8 patients with dyskinetic wall motion. Thus, metabolically active myocardium in infarcted areas or periinfarct ischemia can be visualized with F-18 deoxyglucose and stress N-13 ammonia studies.

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: This study was supported in part by grant-in-aid for scientific research 62570390 from the Japanese Ministry of Education, Science and Culture.

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F-18 deoxyglucose and stress N-13 ammonia positron emission tomography in anterior wall healed myocardial infarction

Abstract

Am J Cardiol

Am J Cardiol

Am J Cardiol

Am Heart J

Am J Cardiol

JACC

JACC

JACC

JACC

Differentiation of transiently ischemic from infarcted myocardium by serial imaging after a single dose of thallium-201

Circulation

Myocardial imaging with thallium-201 at rest and during exercise; comparison with coronary arteriography and stress electrocardiography

Circulation

Correlation of postmortem anatomic findings with electrocardiographic changes in patients with myocardial infarction

Circulation

Myocardial infarct size and location in relation to the coronary vascular bed at risk in man

Circulation

Thallium-201 myocardial perfusion scintigrams in the evaluation of aortocoronary saphenous bypass surgery

J Nucl Med

Determination of radionuclide concentrations with positron CT scanning (PETT)

J Nucl Med