Clinical studyArterial calcification and pathology in uremic patients undergoing dialysis☆
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Cited by (291)
Improving Cardiac Outcomes Among Patients With Severe Chronic Kidney Disease: The Quest Continues
2023, JACC: Cardiovascular InterventionsHigh-phosphate induced vascular calcification is reduced by iron citrate through inhibition of extracellular matrix osteo-chondrogenic shift in VSMCs
2019, International Journal of CardiologyCitation Excerpt :Iron effect in protecting elastic lamellae participate in its anti-calcific action since elastinolysis increases elastin calcium affinity [27]. The relevance of elastinolysis in CKD is demonstrated by the evidence that in uremic patients disruption of internal elastic lamina occurs in elastic arteries [28] and that there is thinning and fragmentation of medial elastic fibers [29]. Thus, the iron action on elastinolysis contribute in contrasting high-Pi induced calcification, even though elastinolysis is an early event necessary but not sufficient to induce VC [30].
The Role of Vitamin K in Vascular Calcification
2019, Advances in Chronic Kidney DiseaseRenal osteodystrophy and chronic kidney disease-mineral bone disorder
2019, Principles of Bone BiologyMineral Bone Disorders in Chronic Kidney Disease
2018, Chronic Kidney Disease, Dialysis, and Transplantation: A Companion to Brenner and Rector’s The Kidney
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This study was supported by The Postgraduate Medical Foundation of Australia, a travel grant from the National Heart Foundation of Australia, the Norman Rose Scholarship of Sydney Hospital, the Kidney Foundation of the Rocky Mountain Region, the Veterans Administration Hospital General Research Funds and National Institutes of Health Contracts 1-AM-4-2217, CA-15823, AM-17760 and AM-18890-01.
- 1
From the Departments of Medicine, Pathology and Surgery, The University of Colorado Medical Center, The Veterans Administration Hospital, Denver Colorado.
- 2
From the Departments of Medicine Royal Brisbane Hospital, Brisbane, Australia.
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Present address: The Royal North Shore Hospital, St. Leonards 2065, New South Wales, Australia.