Elsevier

Progress in Cardiovascular Diseases

Volume 23, Issue 4, January–February 1981, Pages 299-319
Progress in Cardiovascular Diseases

Special article
The frequency and prognostic significance of electrocardiographic abnormalities in clinically normal individuals

https://doi.org/10.1016/0033-0620(81)90018-9Get rights and content

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    • Different characteristics and electrophysiological properties between early and late recurrences after acute successful catheter ablation of idiopathic right ventricular outflow tract arrhythmias during long-term follow-up

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      Idiopathic ventricular arrhythmias (VAs) commonly originate from the right ventricular outflow tract (RVOT) in structurally normal hearts, which are typically characterized by electrocardiographic features of left bundle branch block morphology and inferior axis.1,2 The manifestation of RVOT VAs can vary from the presence of frequent premature ventricular complexes (PVCs) to repetitive salvos, nonsustained ventricular tachycardia (VT) and incessant VTs,3 which could lead to various clinical symptoms including palpitation, dyspnea, atypical chest pain, and syncope.4 Although idiopathic RVOT VA is usually considered as a “benign” entity, it has been linked to the development of PVC-associated cardiomyopathy.5

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      The reported prevalence in apparently healthy populations (ie, the populations from which healthy subjects in phase I studies are drawn) is often assessed using standard resting surface ECGs. However, the prevalence in these assessments, which only capture 10 seconds of electrocardiographic information, is lower than that determined via continuous ECG waveform recordings by a factor that could exceed 100-fold.2 Evenson et al3 reported that 2-minute resting surface ECG recordings poorly predict ventricular ectopy on subsequent 24-hour continuous ECG recording.

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    Supported in part by NIH SCOR Grant HL 17651, NHLBI Grant HL 23970, the American Heart Association-Greater Los Angeles Affiliate, and the Medical Research Service of the Veterans Administration.

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