The historical development, cellular electrophysiology and pharmacology of amiodarone☆
References (181)
- et al.
Ten years of experience with amiodarone
Am Heart J
(1983) - et al.
New perspectives in the pharmacologic therapy of cardiac arrhythmias
Prog Cardiovasc Dis
(1980) Amiodarone: Historical development and pharmacologic profile
Am Heart J
(1983)- et al.
Cardiac beta-adrenoceptor modulation by amiodarone
Biochem Pharmacol
(1983) - et al.
The effects of amiodarone, alpha and beta receptor antagonist, on adrenergic transmission in the cat spleen
Biochem Pharmacol
(1976) - et al.
Acute and chronic effects of amiodarone on ventricular refractoriness, intraventricular conduction and ventricular tachycardia induction
J Am Coll Cardiol
(1986) - et al.
Acute and chronic effects of amiodarone on delayed afterdepolarization and triggered automaticity in rabbit ventricular myocardium
Am Heart J
(1987) - et al.
Serum and myocardial kinetics of amiodarone and its major metabolite desethylamiodarone in rabbits
J Pharm Sci
(1984) - et al.
Electrophysiologic effects of desethylamiodarone an active metabolite of amiodarone: Comparison with amiodarone during chronic administration in rabbits
Am Heart J
(1988) - et al.
Electropharmacology of amiodarone: Absence of relationship to serum myocardial and cardiac sarcolemmal membrane drug concentrations
Am Heart J
(1986)
Influence of thyroid hormone levels on the electrical and mechanical properties of rabbit papillary muscle
J Mol Cell Cardiol
(1985)
Amiodarone and thyroid function: Clinical implications during antiarrhythmic therapy
Am Heart J
(1983)
Interaction of amiodarone and desethylamiodarone with solubilized nuclear thyroid hormone receptors
J Am Coll Cardiol
(1987)
Amiodarone-induced ultrastructural changes in the canine myocardial fibers
Am Heart J
(1986)
Modulation by amiodarone of membrane fluidity and ATPase activity in rat brain synaptosomes
Biochem Biophys Res Commun
(1985)
Amiodarone-induced modifications of the phospholipid physical state. A fluorescence polarization study
Biochem Pharmacol
(1986)
Action of amiodarone on guinea-pig heart sodium and potassium-activated adenosine triphosphatase
Biochem Pharmacol
(1972)
Amiodarone: Correlation of serum concentration with suppression of complex ventricular ectopic activity
Am J Cardiol
(1984)
Effects of intravenous amiodarone in patients with inducible repetitive ventricular responses and ventricular tachycardia
Am Heart J
(1984)
Dose-dependent electrophysiologic effects of amiodarone in the immature canine heart
Am J Cardiol
(1983)
Electrophysiologic effects of amiodarone in canine adult and neonatal myocardial and Purkinje fibers
J Am Coll Cardiol
(1985)
Antiarrhythmic efficacy and electrophysiologic actions of amiodarone in patients with life-threatening arrhythmias
Am Heart J
(1982)
Amiodarone for control of sustained ventricular tachyarrhythmias: Clinical and electrophysiological effects in 51 patients
Am J Cardiol
(1982)
Effect of amiodarone on conduction and refractoriness of the His-Purkinje system in the human heart
J Am Coll Cardiol
(1984)
Amiodarone: Clinical efficacy and electrophysiology during long term therapy for recurrent ventricular tachycardia or ventricular fibrillation
N Engl J Med
(1981)
Anti-arrhythmic efficacy and electrophysiologic actions of amiodarone in patients with life-threatening arrhythmias
Am Heart J
(1982)
Control of refractory life-threatening ventricular arrhythmias by amiodarone
Am Heart J
(1981)
Clinical use and pharmacology of amiodarone
Med Clin North Am
(1984)
Amiodarone in refractory life-threatening ventricular arrhythmias
Ann Intern Med
(1983)
Efficacy of amiodarone for refractory supraventricular tachyarrhythmias
Am Heart J
(1983)
Amiodarone: Electrophysiologic actions pharmacokinetics and clinical effects
J Am Coll Cardiol
(1984)
Clinical efficacy of amiodarone as an antiarrhythmic agent
Am J Cardiol
(1976)
The adrenergic antagonism of amiodarone
Biochem Pharmacol
(1976)
Pharmacology of amiodarone, an antianginal drug with a new biological profile
Arzneimittelforschung
(1968)
Récherche dans la série des benzofurannes. VII. Étude pharmacologique préliminaire du butyl-2(diiodo 3′5′-beta-N-diethylaminoethoxy-4′benzoyl)-3 benzofurannes
Arch Int Pharmacodyn Ther
(1962)
Étude clinique d'une nouvelle medication anti-angoreuse
Acta Cardiol(Brux)
(1967)
Récherche dans la série des benzofurannes. XL. Proprieté anti-arrhythmiques de l'amiodarone
Cardiologia
(1969)
The effect of amiodarone, a new anti anginal drug, on cardiac muscle
Br J Pharmacol
(1970)
A study of the pharmacological actions of certain drugs and hormones with a particular reference to cardiac muscle
A third class of antiarrhythmic action? Effects on atrial and ventricular intracellular potentials and other pharmacologic actions on cardiac muscle of MJ1999 and AH3474
Br J Pharmacol
(1970)
Étude clinique de l'amiodarone dans les troubles du rhythme cardiaque
Presse Med
(1970)
Control of tachyarrhythmias associated with Wolff-Parkinson-White syndrome by amiodarone hydrochloride
Am J Cardiol
(1974)
Effects of amiodarone on thyroid function in patients with ischemic heart disease
Br Heart J
(1975)
Effect of amiodarone on serum triiodothyronine, thyroxine and thyrotropin: A drug influencing peripheral metabolism of thyroid hormones
J Clin Invest
(1976)
The effects of altered thyroid state on atrial intracellular potentials
J Physiol
(1970)
Cardiac actions in the dog of a new antagonist of adrenergic excitation which does not produce competitive blockade of adrenoceptors
Br J Pharmacol
(1970)
Opposite effects of amiodarone and beta-blocking agents on cardiac functions under adrenergic stimulation
Arzneimittelforschung
(1972)
Acute effects of amiodarone in the isolated dog heart
Can J Physiol Pharmacol
(1983)
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2011, Anesthesiology ClinicsCitation Excerpt :In 1985, amiodarone gained approval by the US Food and Drug Administration (FDA). However, as harmful effects arose repeatedly, amiodarone was no longer viewed as an ideal antiarrhythmic.17 By the mid-1990s, amiodarone was being used as “reserve antiarrhythmic” when other antiarrhythmic agents failed.
Ranolazine: Déà vu of the amiodarone story
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Supported by grants from the Medical Research Service of the Veterans Administration and the American Heart Association, the Greater Los Angeles Affiliate, Los Angeles.
Copyright © 1989 Published by Elsevier Inc.