Comparison of magnetic resonance real-time imaging of left ventricular function with conventional magnetic resonance imaging and echocardiography☆
Section snippets
Patients
The study was approved by the institutional review committee of Humboldt University, Berlin. Forty patients were included in the study after giving written informed consent. Five had to be excluded because of a nondiagnostic echocardiogram due to insufficient image quality, and 1 patient was excluded because of claustrophobia in the magnetic resonance scanner; thus, the study consisted of 34 patients. The study group had the following characteristics: 21 men and 13 women, aged 57 ± 13 years
Results
The real-time technique image quality and contrast between blood and the endocardium were sufficient in all 34 patients for contour detection and evaluation of end-diastolic volume, end-systolic volume, and muscle mass. The results are given in Table 2. For end-diastolic volume, end-systolic volume, and ejection fraction, a close correlation between the results of real-time compared with turbo gradient imaging was found (r >0.95). The correlations as well as absolute and mean relative
Discussion
With the new real-time MRI technique, it was possible to acquire high-quality images of the beating heart in real-time with a temporal resolution of 62 ms without electrocardiographic triggering. Real-time images yielded sufficient image quality, with a high contrast between blood and the endocardium, to enable quantitative assessment of LV volumes, muscle mass, and ejection fraction. Compared with the reference standard, determination of end-diastolic and end-systolic volumes and ejection
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This study was supported by Philips Medical Systems, Hamburg, Germany, and Philips Medical Systems, Best, The Netherlands.