MethodsPreejectional Left Ventricular Wall Motion in Normal Subjects Using Doppler Tissue Imaging and Correlation With Ejection Fraction
Section snippets
Study Population
The study group comprised 22 normal subjects who had no cardiac abnormality at clinical, electrocardiographic, and Doppler echocardiographic examinations. Of these, 16 subjects (9 men and 7 women, mean age 37 ± 13 years, range 18 to 65) responding to optimal imaging requirements were studied. No subject had treatment, arrhythmias, or conduction defects. Mean arterial blood pressure was normal in all subjects (mean value 92 ± 10 mm Hg).
Echo Doppler Examination Apparatus
The equipment consisted of a wide angle, phased-array
General Findings
Feasibility was 73% with satisfactory encoding of both walls in 16 cases. The percent of variation was 1.8 ± 20 for reproducibility of velocities. The percent of error was 3 ± 10 (Pk V), 3 ± 8 (Dur) and 9 ± 15 (Pk V), 2 ± 7 (Dur) for intra- and interobserver variabilities respectively (NS). Heart rate was 71 ± 11 beats/min, and LVEF 65 ± 6%.
DTI Findings
Agreement was found for total duration between flow and DTI methods (flow traces 109 ± 13 ms, DTI septum 104 ± 13 ms, posterior wall 107 ± 12 ms, mean
Discussion
For the first time, a DTI study exclusively dedicated to PEP cardiac wall events has been achieved. Phasic strip-by-strip velocity reversals and their respective timing and duration guided an in-depth insight of both cardiac wall PEP mechanical events. Furthermore, the relation of velocities of the posterior wall inward motion with LVEF turn out to be a new finding, suggesting that both the posterior wall and velocities of its inward motion might be of higher value for clinical assessment of LV
Acknowledgements
We wish to express our sincere thanks to John Storey for his help with the English language; Patrick Vanesshe, Faculté de Médecine Paris-Sud, for his efficient image computer assistance; and Claudie Branchard, Chantal Le Bellec, and Nadine Chevallier for their technical and secretarial assistance.
References (30)
- et al.
Left ventricular ejection period; measurement by atraumatic techniques: results in normal young men and comparison of methods of calculation
Am Heart J
(1968) - et al.
Bedside technics for the evaluation of ventricular function in man
Am J Cardiol
(1969) - et al.
Right and left ventricular systolic time intervals. Effect of heart rate, respiration and atrial pacing
Am J Cardiol
(1971) - et al.
Color Doppler myocardial imaging: a new technique for the assessment of myocardial function
J Am Soc Echocardiogr
(1994) - et al.
New method for evaluating left ventricular wall motion by color-coded tissue Doppler imaging: in vitro and in vivo studies
J Am Coll Cardiol
(1995) - et al.
Myocardial velocity gradient as a new indicator of regional left ventricular contraction: detection by a two-dimensional tissue Doppler imaging technique
J Am Coll Cardiol
(1995) - et al.
Quantitative Doppler tissue imaging of the left ventricular myocardium
Am Heart J
(1995) - et al.
Doppler tissue imaging: Myocardial wall motion velocities in normal subjects
J Am Soc Echocardiogr
(1995) - et al.
Myocardial wall velocity assessment by pulsed Doppler tissue imaging: characteristic findings in normal subjects
Am Heart J
(1996) - et al.
The relation of age to the duration of contraction, ejection, and relaxation of the normal human heart
Am Heart J
(1964)
Mitral annular descent velocity by tissue Doppler echocardiography as an index of global left ventricular function
Am J Cardiol
Interdependence of the left and right ventricles in health and disease
Am Heart J
Effects of adrenergic receptor activation and blockade on the systolic pre-ejection period, heart rate and arterial pressure in man
J Clin Invest
Studies on the consecutive phases of the cardiac cycle. I. The duration of the consecutive phases of the cardiac cycle and the criteria for their precise determination
Am J Physiol
Direct correlation of external systolic time intervals with internal indices of left ventricular function in man
Circulation
Cited by (47)
Ultra-high frame rate tissue doppler imaging
2014, Ultrasound in Medicine and BiologyCitation Excerpt :This is in accordance with the studies by Remme et al. (2008), Tsakiris et al. (1978) and Goetz et al. (2005). Pre-ejection velocities have previously been studied by pulsed tissue Doppler as well as color Doppler with high frame rates (Garcia et al. 1996; Pellerin et al. 1997; Pislaru et al. 2001; Sengupta 2005). However, to our knowledge, only Kanai (2009) has examined the basal velocities from the apical view at similar frame rates.
Transmural Myocardial Mechanics During Isovolumic Contraction
2009, JACC: Cardiovascular ImagingReduced systolic performance by tissue Doppler in patients with preserved and abnormal ejection fraction: New insights in chronic heart failure
2006, International Journal of CardiologyLongitudinal isovolumic displacement of the left ventricular myocardium assessed by tissue velocity echocardiography in healthy individuals
2006, Journal of the American Society of EchocardiographyRenewed interest in preejectional isovolumic phase: New applications of tissue doppler indexes: Implications to ventricular dyssynchrony
2005, American Journal of CardiologyDetection of prominent left anterior descending coronary artery stenosis for patients with stable angina using Doppler tissue echocardiography
2005, Journal of the American Society of Echocardiography