Congestive Heart FailureHemodynamic Profile of Submaximal Constant Workload Exercise in Patients With Heart Failure Secondary to Ischemic or Idiopathic Dilated Cardiomyopathy
Section snippets
Study Group:
We studied 21 male patients (mean age 59 ± 8 years, range 46 to 72) in sinus rhythm with chronic heart failure of at least 6 months duration caused by left ventricular systolic dysfunction. Mean value of left ventricular ejection fraction was 24 ± 8% (range 13% to 35%), as assessed by means of 2-dimensional echocardiography or radionuclide ventriculography. The etiology of heart failure was coronary artery disease in 12 patients and idiopathic dilated cardiomyopathy in 9. Twelve patients were
Results
Table I lists the hemodynamics in the sitting position before the maximal exercise test and before every submaximal constant-load exercise. The resting hemodynamic profile was similar in the 3 conditions. Table II lists the hemodynamic responses observed during the symptom-limited exercise test.
Discussion
In the last decade, there has been a growing interest in submaximal exercise tests in the functional evaluation of heart failure patients. In these patients, exercise performed at submaximal workload seems to be better tolerated than exercise performed at the maximal workload, and seems to be a more consistent indicator of functional limitation during daily activities, which usually are not symptom-limited. Furthermore, exercise performed at selected submaximal constant work rates represents
Acknowledgements
Acknowledgment:
We are indebted to Marco Pagani for assistance in statistical analysis and Paola Musatti, RN, for extensive support during this study. We also thank Simonetta Scalvini, MD, and Maurizio Volterrani, MD, who cared for patients included in this study, and the patients themselves.
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