Clinical study: hypertensionEffect of the angiotensin-converting enzyme inhibitor imidapril on reactive hyperemia in patients with essential hypertension: relationship between treatment periods and resistance artery endothelial function☆
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Abbreviations
ACE
angiotensin-converting enzyme
BP
blood pressure
EDHF
endothelium-dependent hyperpolarizing factor
FBF
forearm blood flow
FVR
forearm vascular resistance
L-NMMA
NG-monomethyl-L-arginine
NO
nitric oxide
NTG
nitroglycerin
RH
reactive hyperemia
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This study was supported in part by a Grant-in-Aid for Scientific Research from the Ministry of Education, Science and Culture of Japan, Tokyo, Japan (Dr. Oshima) and the Japan Heart Foundation Grant for Research on Hypertension and Metabolism, Tokyo, Japan; a Grant for Research Foundation for Community Medicine, Tokyo, Japan; a Grant for Research on Autonomic Nervous System and Hypertension from Kimura Memorial Heart Foundation/Pfizer Pharmaceuticals Inc., Kwume, Japan; and the Foundation for Total Health Promotion, Tokyo, Japan (Dr. Higashi).
Copyright © 2001 American College of Cardiology. Published by Elsevier Inc. All rights reserved.