Journal of the American Society of Echocardiography
Age Dependency of Left Atrial and Left Ventricular Acoustic Quantification Waveforms for the Evaluation of Diastolic Performance in Left Ventricular Hypertrophy☆,☆☆,★
Section snippets
Study Subjects
Fifty normal subjects (10 subjects in each decade from the fourth to the eighth) served as the control group. These subjects comprised both volunteers and patients referred to the echocardiographic laboratory. All subjects were without a history of systemic hypertension and normotensive at the time of their echocardiographic examination. All control subjects had normal LV systolic performance without regional wall motion abnormalities and a normal LV mass index with no more than trivial aortic
RESULTS
The average age in both groups was 55 years old. The LV masses were 128 ± 33 g (index 69 ± 15 g/m2 ) and 307 ± 103 g (index 170 ± 56 g/m2 ) in the control and LVH group, respectively. There were no intergroup differences in heart rate (71 ± 10 vs 74 ± 11).
DISCUSSION
Acoustic quantification, a technique based on integrated backscatter analysis, allows detection of the blood-tissue interface. This provides automated real-time acquisition of ventricular and atrial area waveforms over time. Although this technique has been extensively validated for the evaluation of LV systolic function, few studies have used this methodology to assess LV diastolic performance. Previous studies have been limited by both the small number of patients in the control groups (fewer
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Cited by (0)
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From the Noninvasive Cardiac Imaging Laboratories, Department of Medicine, Section of Cardiology, University of Chicago.
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Reprint requests: Kirk T. Spencer, MD, Department of Medicine, Section of Cardiology, University of Chicago, 5841 South Maryland Ave, MC5084, Chicago, IL 60637.
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