Original articleAdult cardiacPatient-Prosthesis Mismatch in Patients With Aortic Stenosis Undergoing Isolated Aortic Valve Replacement Does Not Affect Survival
Section snippets
Material and Methods
This study was approved by University Hospital Birmingham NHS Foundation Trust Research and Development Board (Project no. CA2–02355).
Results
Summary patient demographics, type of operation, and mismatch group are summarized in Table 1, Table 2. PPM was severe in 48 patients (6.0%) and moderate in 462 (57.8%). The remaining 291 patients (36.4%) had no PPM and were defined as the reference group. Mismatch was associated with increasing age and female gender, thus resulting in an increase in the mean EuroSCORE (reference group, 4.9 ± 2.6; moderate PPM, 5.8 ± 2.4; and severe PPM 6.1 ± 2.1; p < 0.001).
Despite the increasing operative
Comment
The main finding of this study is that although moderate mismatch was common, severe mismatch was rare, affecting only 6% of patients, and there was no significant adverse effect on in-hospital mortality or late survival in either mismatch group compared with the reference group irrespective of age, patient body mass index, or systolic function. The similar survival between the different mismatch groups was noted, despite the mismatch groups having a progressive increase in risk profile mainly
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