Original InvestigationPathogenesis and Treatment of Kidney DiseaseGFR and Cardiovascular Outcomes After Acute Myocardial Infarction: Results From the Korea Acute Myocardial Infarction Registry
Section snippets
Korea AMI Registry
The Korea AMI Registry (KAMIR) is a prospective multicenter online registry designed to describe characteristics and clinical outcomes of patients with AMI and reflects current management of patients with AMI in Korea. The registry included 52 community and university hospitals with the capability of primary percutaneous coronary intervention (PCI). Data were collected retrospectively at each site by a trained study coordinator based on a standardized protocol. We analyzed the enrolled data to
Baseline Characteristics
A total of 12,636 patients were included in the present study; 3,491 (27.6%) patients with eGFR >90 mL/min/1.73 m2; 5,791 (45.8%) with eGFR of 60-89 mL/min/1.73 m2; 2,609 (20.6%) with eGFR of 30-59 mL/min/1.73 m2; 439 (3.5%) with eGFR of 15-29 mL/min/1.73 m2; and 306 (2.4%) with eGFR <15 mL/min/1.73 m2; 61.6% had STEMI; and 39.4% had NSTEMI. Table 1 lists baseline characteristics of patients by eGFR category at baseline. Overall, median follow-up was 404 days, mean age was 64 years, 70.4% were
Discussion
Cardiovascular disease in patients with CKD is common and has major implications in terms of both human suffering and health care cost. The present study evaluated prognostic factors and clinical outcomes of patients experiencing AMI by eGFR level. Interestingly, STEMI was more common in patients with higher eGFR category, whereas the prevalence of NSTEMI was higher in patients with lower eGFR category, as previously shown by others.16 These findings may suggest that loss of kidney function is
Acknowledgements
Support: This research was supported by Basic Science Research Program through the National Research Foundation of Korea funded by the Ministry of Education, Science and Technology (2010-0008732), and by the Korea Science and Engineering Foundation through the Medical Research Center for Gene Regulation (grant 2011-0030732) at Chonnam National University.
Financial Disclosure: The authors declare that they have no other relevant financial interests.
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Originally published online March 26, 2012.
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E.H.B. and S.Y.L. contributed equally to this work.