Management of labor in Eisenmenger syndrome with inhaled nitric oxide

Am J Obstet Gynecol. 1999 Aug;181(2):419-23. doi: 10.1016/s0002-9378(99)70572-7.

Abstract

Administration of nitric oxide by means of inhalation during the labor of a woman with Eisenmenger's syndrome caused by an atrial septal defect resulted in improved oxygenation and initial pulmonary arterial pressure. She gave birth to a live infant at 34 weeks' gestation but died of worsening pulmonary hypertension and heart failure 21 days post partum.

Publication types

  • Case Reports

MeSH terms

  • Administration, Inhalation
  • Adult
  • Bed Rest
  • Eisenmenger Complex / complications*
  • Eisenmenger Complex / therapy
  • Female
  • Gestational Age
  • Heparin / therapeutic use
  • Humans
  • Labor, Obstetric*
  • Nitric Oxide / administration & dosage*
  • Nitric Oxide / therapeutic use
  • Oxygen / administration & dosage
  • Oxytocin / therapeutic use
  • Postpartum Hemorrhage / drug therapy
  • Pregnancy
  • Pregnancy Complications, Cardiovascular* / therapy

Substances

  • Nitric Oxide
  • Oxytocin
  • Heparin
  • Oxygen