Fatal cerebral hemorrhage and severe thrombocytopenia during abciximab treatment

B Vahdat; I Canavy; L Fourcade; E Garcia; J Quilici; J L Bonnet; M Bory

doi:10.1002/(sici)1522-726x(200002)49:2<177::aid-ccd13>3.0.co;2-j

Fatal cerebral hemorrhage and severe thrombocytopenia during abciximab treatment

Catheter Cardiovasc Interv. 2000 Feb;49(2):177-80. doi: 10.1002/(sici)1522-726x(200002)49:2<177::aid-ccd13>3.0.co;2-j.

Authors

B Vahdat¹, I Canavy, L Fourcade, E Garcia, J Quilici, J L Bonnet, M Bory

Affiliation

¹ Department A of Cardiology, La Timone Hospital, University of Marseille, France.

PMID: 10642768
DOI: 10.1002/(sici)1522-726x(200002)49:2<177::aid-ccd13>3.0.co;2-j

Abstract

We describe the case of a fatal cerebral hemorrhage associated with a severe thrombocytopenia (4.0 x 10(9)/l), occurring only 90 min after starting treatment with abciximab, in a patient undergoing primary percutaneous transluminal coronary angioplasty (PTCA) for an acute myocardial infarction. Cathet. Cardiovasc. Intervent. 49:177-180, 2000.

Publication types

Case Reports

MeSH terms

Abciximab
Angioplasty, Balloon, Coronary
Antibodies, Monoclonal / adverse effects*
Cerebral Hemorrhage / chemically induced*
Cerebral Hemorrhage / diagnostic imaging
Coronary Angiography
Fatal Outcome
Female
Humans
Immunoglobulin Fab Fragments / adverse effects*
Middle Aged
Myocardial Infarction / diagnostic imaging
Myocardial Infarction / therapy
Platelet Aggregation Inhibitors / adverse effects*
Platelet Glycoprotein GPIIb-IIIa Complex / antagonists & inhibitors*
Thrombocytopenia / chemically induced*
Thrombocytopenia / complications
Thrombosis / prevention & control
Tomography, X-Ray Computed

Substances

Antibodies, Monoclonal
Immunoglobulin Fab Fragments
Platelet Aggregation Inhibitors
Platelet Glycoprotein GPIIb-IIIa Complex
Abciximab