Abnormal brachial artery flow-mediated vasodilation in young adults with major depression

Am J Cardiol. 2001 Jul 15;88(2):196-8, A7. doi: 10.1016/s0002-9149(01)01623-x.

Abstract

Depressive illness in patients without traditional risk factors for coronary artery disease is associated with striking abnormalities of endothelial function and elevation of circulating markers of atherosclerosis propensity. Further studies are needed to define the mechanisms that underlie these observations.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, P.H.S.

MeSH terms

  • Adult
  • Brachial Artery / physiopathology*
  • Case-Control Studies
  • Chemokine CCL2 / analysis
  • Coronary Disease / epidemiology
  • Depressive Disorder / physiopathology*
  • E-Selectin / analysis
  • Endothelium, Vascular / physiopathology
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Hyperemia / physiopathology
  • Intercellular Adhesion Molecule-1 / analysis
  • Male
  • Risk Factors
  • Vascular Cell Adhesion Molecule-1 / analysis
  • Vasodilation / physiology*

Substances

  • Chemokine CCL2
  • E-Selectin
  • Vascular Cell Adhesion Molecule-1
  • Intercellular Adhesion Molecule-1