Effect of clopidogrel pretreatment on periprocedural rise in C-reactive protein after percutaneous coronary intervention

Am J Cardiol. 2004 Aug 1;94(3):358-60. doi: 10.1016/j.amjcard.2004.04.035.

Abstract

This study sought to determine the effect of clopidogrel pretreatment on the increase in C-reactive protein (CRP) after percutaneous coronary intervention. Clopidogrel pretreatment attenuated the periprocedural increase in CRP by 65% and was independently associated with an attenuation in the CRP increase in a multivariate model.

Publication types

  • Comparative Study

MeSH terms

  • Adult
  • Aged
  • Angioplasty, Balloon, Coronary / methods*
  • C-Reactive Protein / analysis
  • C-Reactive Protein / drug effects*
  • Case-Control Studies
  • Clopidogrel
  • Cohort Studies
  • Coronary Angiography
  • Coronary Disease / diagnostic imaging
  • Coronary Disease / drug therapy*
  • Coronary Disease / therapy
  • Coronary Restenosis / prevention & control*
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Linear Models
  • Male
  • Middle Aged
  • Multivariate Analysis
  • Platelet Aggregation Inhibitors / administration & dosage
  • Reference Values
  • Risk Assessment
  • Severity of Illness Index
  • Ticlopidine / administration & dosage*
  • Ticlopidine / analogs & derivatives*
  • Treatment Outcome

Substances

  • Platelet Aggregation Inhibitors
  • C-Reactive Protein
  • Clopidogrel
  • Ticlopidine