Immunohistology of bone marrow: a modified method of glycol-methacrylate embedding

Histopathology. 1991 Jan;18(1):37-43. doi: 10.1111/j.1365-2559.1991.tb00812.x.

Abstract

We describe here a modified glycol-methacrylate embedding technique for bone marrow biopsies which allows high-quality visualization of morphological details and optimal antigen preservation. By the use of this technique it is possible to recognize haemopoietic and stromal cells which are known to play a key role in the regulation of haemopoiesis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Anemia, Aplastic / diagnosis
  • Anemia, Aplastic / metabolism
  • Anemia, Aplastic / pathology
  • Antibodies, Monoclonal
  • Biopsy
  • Bone Marrow / metabolism*
  • Bone Marrow / pathology
  • Bone Marrow Cells
  • Child
  • Child, Preschool
  • Female
  • Glycols*
  • Histological Techniques
  • Humans
  • Immunohistochemistry
  • Male
  • Methacrylates*
  • Middle Aged

Substances

  • Antibodies, Monoclonal
  • Glycols
  • Methacrylates