The prophylactic use of octreotide in a patient with ovarian carcinoid and valvular heart disease

Can J Anaesth. 1990 Oct;37(7):798-800. doi: 10.1007/BF03006540.

Abstract

This case report describes the use of octreotide, a long-acting somatostatin analogue, in the management of a patient with an ovarian carcinoid tumour and severe cardiac valvular disease. This patient underwent laparotomy and tumour resection without complication. Anaesthesia was induced with midazolam, fentanyl, and vecuronium, and maintained with isoflurane as well as additional fentanyl and vecuronium. However, we feel that it was the use of octreotide that prevented a life-threatening crisis intraoperatively, and recommend its use in patients with carcinoid syndrome undergoing anaesthesia and surgery.

Publication types

  • Case Reports

MeSH terms

  • Anesthesia, Inhalation
  • Anesthesia, Intravenous
  • Carcinoid Tumor / complications
  • Carcinoid Tumor / surgery*
  • Female
  • Heart Valve Diseases / complications*
  • Humans
  • Intraoperative Complications / prevention & control
  • Middle Aged
  • Octreotide / therapeutic use*
  • Ovarian Neoplasms / complications
  • Ovarian Neoplasms / surgery*
  • Premedication*
  • Ranitidine / therapeutic use

Substances

  • Ranitidine
  • Octreotide