Life-threatening pulmonary embolism with right-sided heart thrombus. Rapid recovery with recombinant tissue plasminogen activator

C d'Ivernois; P Le Metayer; B Fischer; M Haissaguerre; J F Warin

doi:10.1378/chest.105.4.1291

Life-threatening pulmonary embolism with right-sided heart thrombus. Rapid recovery with recombinant tissue plasminogen activator

Chest. 1994 Apr;105(4):1291-2. doi: 10.1378/chest.105.4.1291.

Authors

C d'Ivernois¹, P Le Metayer, B Fischer, M Haissaguerre, J F Warin

Affiliation

¹ Service de Cardiologie et Médicine Interne, Hôpital Saint-André, Bordeaux, France.

PMID: 8162778
DOI: 10.1378/chest.105.4.1291

Abstract

We report the case of a woman treated with urokinase for acute pulmonary embolism with a right-sided heart thrombus. She developed life-threatening acute cor pulmonale which dramatically improved within 4 h with recombinant tissue plasminogen activator (rtPA). We emphasize the clinical interest of rtPA for the treatment of life-threatening pulmonary embolism.

Publication types

Case Reports

MeSH terms

Acute Disease
Adult
Echocardiography
Female
Heart Diseases / complications*
Heart Diseases / diagnostic imaging
Heart Diseases / drug therapy
Humans
Pulmonary Embolism / complications*
Pulmonary Embolism / drug therapy
Recombinant Proteins / therapeutic use
Thrombolytic Therapy
Thrombosis / complications*
Thrombosis / diagnostic imaging
Thrombosis / drug therapy
Tissue Plasminogen Activator / therapeutic use*
Urokinase-Type Plasminogen Activator / therapeutic use

Substances

Recombinant Proteins
Tissue Plasminogen Activator
Urokinase-Type Plasminogen Activator