Developments and advances in surgical and anesthetic techniques have lead to increased survival in patients undergoing complex thoracic aortic aneurysm repairs. The decision to operate, however, continues to be based in a large degree on the clinical impression of the patient's ability to withstand the rigors of the procedure. As part of the ongoing effort of our department to further elucidate those parameters that impart added risk to patients, the diameters and volumes of CT-imaged aortas were determined for 67 surgical and nonoperatively managed patients. Significant differences were found between those patients not requiring surgery, and both those undergoing operation and those that died of rupture. Similarly, the average yearly increase in volume in surgical and rupture patients was higher than that of nonoperatively managed patients. Those patients who smoked also were found to have a significant yearly increase in size of their aortas relative to those patents that did not. An algorithm for managing patients presenting with thoracoabdominal aneurysms based upon size at initial presentation, change in annual diameter and volume, and estimated risk for paraplegia is presented.