Abstract
The arterial wall reaction to phosphorylcholine-coated metal stents was examined in rabbits and pigs. Compared to non-coated stents, no significant difference was found by angiography and histology. We conclude that although phosphorylcholine-coating does not provoke arterial neointima formation or decrease luminal diameter compared to stainless steel stents, the coating does not seem to reduce restenosis.
Publication types
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Comparative Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Angiography
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Animals
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Arteries / pathology*
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Arteries / surgery*
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Blood Vessel Prosthesis Implantation / instrumentation*
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Blood Vessel Prosthesis Implantation / methods
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Coated Materials, Biocompatible*
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Coronary Angiography
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Coronary Vessels / pathology
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Coronary Vessels / surgery
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Culture Techniques
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Disease Models, Animal
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Iliac Artery / diagnostic imaging
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Iliac Artery / surgery
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Male
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Materials Testing
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Metals
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Phosphorylcholine* / chemistry
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Rabbits
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Reference Values
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Stents*
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Swine
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Swine, Miniature
Substances
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Coated Materials, Biocompatible
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Metals
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Phosphorylcholine