The roles of gender, the menopause and hormone replacement on cardiovascular function

CS Hayward, RP Kelly, P Collins - Cardiovascular research, 2000 - academic.oup.com
While it is recognised that gender differences exist in Because of the higher cardiac mortality
in men comcardiovascular disease, it has only recently been ap- pared to women until late …

Gender-related differences in left ventricular chamber function

CS Hayward, WV Kalnins, RP Kelly - Cardiovascular research, 2001 - academic.oup.com
Objectives: While women have lower rates of atherosclerotic disease than men, they are
more likely to suffer cardiac failure following infarction or cardiac surgery, despite typically …

Effect of sex hormones on cardiac mass

CS Hayward, CM Webb, P Collins - The Lancet, 2001 - thelancet.com
Increased left-ventricular mass is an important cardiovascular risk factor for morbidity and
mortality. Apart from obvious differences in cardiac size, the changes in left-ventricular mass …

Effects of testosterone on coronary vasomotor regulation in men with coronary heart disease

CM Webb, JG McNeill, CS Hayward, D De Zeigler… - Circulation, 1999 - Am Heart Assoc
Background—The increased incidence of coronary artery disease in men compared with
premenopausal women suggests a detrimental role of male hormones on the cardiovascular …

Integrated allelic, transcriptional, and phenomic dissection of the cardiac effects of titin truncations in health and disease

AM Roberts, JS Ware, DS Herman, S Schafer… - Science translational …, 2015 - science.org
The recent discovery of heterozygous human mutations that truncate full-length titin (TTN, an
abundant structural, sensory, and signaling filament in muscle) as a common cause of end …

Gender-related differences in the central arterial pressure waveform

CS Hayward, RP Kelly - Journal of the American College of Cardiology, 1997 - jacc.org
Objectives. This study investigated the effect of age and gender on central arterial
hemodynamic variables derived from noninvasive tonometric carotid pressure waveforms …

Parenteral administration of recombinant human neuregulin‐1 to patients with stable chronic heart failure produces favourable acute and chronic haemodynamic …

A Jabbour, CS Hayward, AM Keogh… - European journal of …, 2011 - Wiley Online Library
Aims Neuregulin‐1 (NRG‐1) plays a critical role in the adaptation of the heart to injury,
inhibiting apoptosis and inducing cardiomyocyte proliferation. We have shown previously …

Differences between beta-blockers in patients with chronic heart failure and chronic obstructive pulmonary disease: a randomized crossover trial

A Jabbour, PS Macdonald, AM Keogh, E Kotlyar… - Journal of the American …, 2010 - jacc.org
Objectives: The purpose of this study was to determine the respiratory, hemodynamic, and
clinical effects of switching between β1-selective and nonselective beta-blockers in patients …

Assessment of endothelial function using peripheral waveform analysis: a clinical application

CS Hayward, M Kraidly, CM Webb, P Collins - Journal of the American …, 2002 - jacc.org
Objectives: The study was done to determine whether radial artery applanation tonometry
can be used as a noninvasive method of assessing global endothelial function. Background …

The prevalence and prognostic significance of frailty in patients with advanced heart failure referred for heart transplantation

SR Jha, MK Hannu, S Chang, E Montgomery… - …, 2016 - journals.lww.com
Background Frailty is a clinically recognized syndrome of decreased physiological reserve.
The heightened state of vulnerability in these patients confers a greater risk of adverse …