Background Widening of socioeconomic status (SES) inequalities in smoking prevalence
has occurred in several Western countries from the mid 1970's onwards. However, little is …

Study objective The potential of perioperative goal-directed therapy (PGDT) to improve
outcome after high-risk abdominal surgery remains subject of debate. In particular, there is a …

In this prospective, interventional, international study, we investigate continuous monitoring
of hospitalised patients' vital signs using wearable technology as a basis for real-time early …

Background: All European countries need to increase the number of health professionals in
the near future. Most efforts have not brought the expected results so far. The current notion …

This study introduces machine learning predictive models to predict the future values of the
monitored vital signs of COVID-19 ICU patients. The main vital sign predictors include heart …

Background Hydroxyethyl starch (HES) solutions are used for volume therapy to treat
hypovolemia due to acute blood loss and to maintain hemodynamic stability. This study was …

Background: Subthalamic nucleus (STN) deep brain stimulation (DBS) has become a
routine treatment of advanced Parkinson's disease (PD). DBS surgery is commonly …

Objective To investigate whether smoke-free legislation in the Netherlands led to a
decreased incidence of out-of-hospital sudden circulatory arrest (SCA). Smoke-free …

Background Perioperative complications occur in 30–40% of non-cardiac surgical patients
and are the leading cause of early postoperative morbidity and mortality. Regular visits by …

Introduction During the COVID-19 pandemic many non-acute elective surgeries were
cancelled or postponed around the world. This has created an opportunity to study the effect …