RoB 2: a revised tool for assessing risk of bias in randomised trials

JAC Sterne, J Savović, MJ Page, RG Elbers… - bmj, 2019 - bmj.com
Assessment of risk of bias is regarded as an essential component of a systematic review on
the effects of an intervention. The most commonly used tool for randomised trials is the …

[HTML][HTML] COVID-19 pandemic and admission rates for and management of acute coronary syndromes in England

MM Mafham, E Spata, R Goldacre, D Gair, P Curnow… - The Lancet, 2020 - thelancet.com
Background Several countries affected by the COVID-19 pandemic have reported a
substantial drop in the number of patients attending the emergency department with acute …

Do selective cyclo-oxygenase-2 inhibitors and traditional non-steroidal anti-inflammatory drugs increase the risk of atherothrombosis? Meta-analysis of randomised …

PM Kearney, C Baigent, J Godwin, H Halls… - Bmj, 2006 - bmj.com
Objective To assess the effects of selective cyclo-oxygenase-2 (COX 2) inhibitors and
traditional non-steroidal anti-inflammatory drugs (NSAIDs) on the risk of vascular events …

Effect of alcohol on risk of coronary heart disease and stroke: causality, bias, or a bit of both?

JR Emberson, DA Bennett - Vascular health and risk management, 2006 - Taylor & Francis
Epidemiological studies of middle-aged populations generally find the relationship between
alcohol intake and the risk of coronary heart disease (CHD) and stroke to be either U-or J …

Comparison of risk prediction using the CKD-EPI equation and the MDRD study equation for estimated glomerular filtration rate

K Matsushita, BK Mahmoodi, M Woodward… - Jama, 2012 - jamanetwork.com
Context The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation more
accurately estimates glomerular filtration rate (GFR) than the Modification of Diet in Renal …

[HTML][HTML] Impact of diabetes on the effects of sodium glucose co-transporter-2 inhibitors on kidney outcomes: collaborative meta-analysis of large placebo-controlled …

C Baigent, JR Emberson, R Haynes, WG Herrington… - The Lancet, 2022 - thelancet.com
Background Large trials have shown that sodium glucose co-transporter-2 (SGLT2)
inhibitors reduce the risk of adverse kidney and cardiovascular outcomes in patients with …

Casirivimab and imdevimab in patients admitted to hospital with COVID-19 (RECOVERY): a randomised, controlled, open-label, platform trial

RECOVERY Collaborative Group, PW Horby… - Medrxiv, 2021 - medrxiv.org
Background REGEN-COV is a combination of 2 monoclonal antibodies (casirivimab and
imdevimab) that bind to two different sites on the receptor binding domain of the SARS-CoV …

Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

P Akbari, A Gilani, O Sosina, JA Kosmicki, L Khrimian… - Science, 2021 - science.org
INTRODUCTION Obesity accounts for a substantial and growing burden of disease globally.
Body adiposity is highly heritable, and human genetic studies can lead to biological and …

2022 Joint ESC/EACTS review of the 2018 guideline recommendations on the revascularization of left main coronary artery disease in patients at low surgical risk and …

RA Byrne, S Fremes, D Capodanno… - European Journal of …, 2023 - academic.oup.com
Task Force structure and summary of clinical evidence of 2022 ESC/EACTS review of the
2018 guideline recommendations on the revascularization of left main coronary artery …

Passive smoking and risk of coronary heart disease and stroke: prospective study with cotinine measurement

PH Whincup, JA Gilg, JR Emberson, MJ Jarvis… - Bmj, 2004 - bmj.com
Objective To examine the associations between a biomarker of overall passive exposure to
tobacco smoke (serum cotinine concentration) and risk of coronary heart disease and stroke …