Brugada syndrome is a rare inherited arrhythmia syndrome leading to an increased risk of
sudden cardiac death, despite a structurally normal heart. Diagnosis is based on a specific …

For the last 10 years, applying new sequencing technologies to thousands of whole exomes
has revealed the high variability of the human genome. Extreme caution should thus be …

Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A
mutations in around 20% of cases,,. Through a genome-wide association study of 312 …

Background—Implantable cardioverter-defibrillator indications in Brugada syndrome remain
controversial, especially in asymptomatic patients. Previous outcome data are limited by …

Brugada syndrome (BrS) is a cardiac arrhythmia disorder associated with sudden death in
young adults. With the exception of SCN5A, encoding the cardiac sodium channel NaV1. 5 …

Introduction: Atrial fibrillation (AF) is the most frequent arrhythmia worldwide. While mostly
seen in elderly, it can also affect young adults (≤ 45 years of age), older adolescent, and …

Background: Mitral valve prolapse (MVP) is a frequent disease that can be complicated by
mitral regurgitation (MR), heart failure, arterial embolism, rhythm disorders, and death. Left …

Background: Long QT syndrome (LQTS) is a rare genetic disorder and a major preventable
cause of sudden cardiac death in the young. A causal rare genetic variant with large effect …

Abstract The Brugada syndrome (BrS) is a rare heritable cardiac arrhythmia disorder
associated with ventricular fibrillation and sudden cardiac death. Mutations in the SCN5A …

Prevalence and prognostic value of conduction disturbances in patients with the Brugada
syndrome (BrS) remains poorly known. Electrocardiograms (ECGs) from 325 patients with …