Preeclampsia is a complication of pregnancy manifested as maternal hypertension and
often fetal growth restriction. Placental ischemia could be an initiating event, but the linking …

Preeclampsia is a pregnancy-related disorder characterized by hypertension with an
unclear mechanism. Studies have shown endothelial dysfunction and increased endothelin …

Normal pregnancy is associated with adaptive hemodynamic, hormonal, and vascular
changes, and estrogen (E2) may promote vasodilation during pregnancy; however, the …

Estrogen interacts with estrogen receptors (ERs) to induce vasodilation, but the ER subtype
and post-ER relaxation pathways are unclear. We tested if ER subtypes mediate distinct …

Preeclampsia is a pregnancy-related disorder manifested as maternal hypertension in
pregnancy (HTN-Preg) and fetal growth restriction. Placental ischemia could be an initiating …

Progress in understanding the pathophysiology of abdominal aortic aneurysms (AAA) is
dependent in part on the development and application of effective animal models that …

Background Abdominal aortic aneurysm (AAA) is characterized by chronic inflammation and
degradation of the extracellular matrix, mediated by matrix metalloproteinases (MMPs) …

Coronary artery aneurysm (CAA) is a neglected topic in the pathology literature; most
descriptions of CAAs have been limited to reports of single cases and some reviews …

Patients with congenital heart disease (CxHD) are surviving into adulthood, as well as living
longer and growing older [1], due the major achievements in their diagnosis, medical man …

Surgeries to correct congenital heart diseases are increasing in Brazil and worldwide.
However, even with the advances in surgical techniques and perfusion, some cases …