Background Elevated proinflammatory cytokines are associated with greater COVID-19
severity. We aimed to assess safety and efficacy of sarilumab, an interleukin-6 receptor …

Objective: To describe the contemporary features of coagulase-negative staphylococcal
(CoNS) prosthetic valve endocarditis (PVE). Design: Observational study of prospectively …

Two-dimensional echocardiography was performed in 29 normotensive obese subjects and
21 hypertensive obese subjects representative of the Chilean population. The left ventricular …

Objectives. This study sought to describe the ability of transesophageal echocardiography
(TEE) to document the presence of penetrating atherosclerotic aortic ulcers and their …

OBJECTIVES: We sought to compare the diagnostic performance of 3-dimensional (3D)
versus 2-dimensional (2D) echocardiography in patients with regurgitant mitral valve …

Aims Arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) is a life-
threatening entity with a highly heterogeneous genetic background. Cardiac magnetic …

Introduction and objectives Missense mutations in the filamin C (FLNC) gene have been
reported as cause of inherited cardiomyopathy. Knowledge of the pathogenicity and …

Background: Rates of morbidity and mortality in Infective Endocarditis (IE) remain high and
prognosis in this disease is still difficult and uncertain. Aim: To study IE in Chile in its active …

BACKGROUND: Infective endocarditis is a severe condition, with a mortality that fluctuates
between 16 and 25% in the Metropolitan area of Chile. AIM: To perform a prospective …

Background: Arrhythmogenic cardiomyopathy (AC) is a life-threatening disease which
predispose to malignant arrhythmias and sudden cardiac death (SCD) in the early stages of …