Cardiovascular disease is a leading cause of morbidity and mortality in individuals with
Down syndrome. Congenital heart disease is the most common cardiovascular condition in …

Background—Adult congenital heart disease (ACHD) patients have ongoing morbidity and
reduced long-term survival. Recently, the importance of specialized follow-up at tertiary …

Background—Parameters of cardiopulmonary exercise testing were recently identified as
strong predictors of mortality in adults with congenital heart disease. We hypothesized that …

Background—Sudden cardiac death and life-threatening ventricular arrhythmia remain a
concern in adult patients with repaired tetralogy of Fallot. Longitudinal left ventricular (LV) …

Aims The population of adults with congenital heart disease (ACHD) is growing and ageing.
Limited information about the diagnostic spectrum of this emerging population, its resource …

Echocardiography is the mainstay in screening for pulmonary hypertension (PH).
International guidelines suggest echocardiographic parameters for suspecting PH, but these …

Background—Restrictive lung defects are associated with higher mortality in patients with
acquired chronic heart failure. We investigated the prevalence of abnormal lung function, its …

Abstract Aims The New York Heart Association functional classification (NYHA class) is often
used to describe the functional capacity of adults with congenital heart disease (ACHD) …

INTRODUCTION: Iron deficiency is common in cyanotic congenital heart disease (CHD) and
results in reduced exercise tolerance. Currently, iron replacement is advocated with limited …

Abstract In the current era, 5%-10% of Fontan patients die or need a transplant in childhood,
and approximately 50% will experience the same fate by age 40 years. Heart transplant …