Decreased exercise tolerance and worsening of angina symptoms during the winter months
is a well-documented phenomenon among patients with coronary artery disease (CAD). 1 …

The phenomenon of warm-up angina was first noted over 200 years ago. It describes the
curious observation whereby exercise-induced ischaemia on second effort is significantly …

Coronary microvascular resistance is increasingly measured as a predictor of clinical
outcomes, but there is no accepted gold-standard measurement. We compared the …

Background Cold air inhalation during exercise increases cardiac mortality, but the
pathophysiology is unclear. During cold and exercise, dual‐sensor intracoronary wires …

The synergistic effect of comorbidity, coronary artery lesion complexity and left ventricular
(LV) systolic function can significantly increase the risk of adverse events at the time of …

• B-type natriuretic peptide (BNP) or N-terminal pro-B-type natriuretic peptide (NT pro-BNP),
as per NICE guidance to assess likelihood of heart failure:-BNP> 400 pg/mL or NT pro …

2. Afterload: MAP against which the LV volume is ejected:• As afterload increases, the
degree of end diastolic stretch of the LV increases, enhancing contractility. Pathologically …

Coronary microvascular resistance is increasingly measured as a predictor of clinical
outcomes, but there is no accepted gold-standard measurement. We compared the …

Creagh-Brown's point that [beta] blockers should be offered to patients with left ventricular
systolic dysfunction and chronic obstructive pulmonary disease without reversibility on …

Brief periods of ischaemia activate systemic mechanisms that induce whole-body tolerance
to subsequent prolonged and injurious ischaemia. This phenomenon, remote ischaemic …