This international consensus statement is the collaborative effort of three medical societies
representing electrophysiology in North America, Europe and Asian-Pacific area: the Heart …

HRS/EHRA/APHRS expert consensus statement on the diagnosis and management of patients
with inherited primary arrhythmia syndromes | EP Europace | Oxford Academic Skip to Main …

The J-wave syndromes (JWSs), consisting of the Brugada syndrome (BrS) and early
repolarization syndrome (ERS), have captured the interest of the cardiology community over …

Brugada syndrome is a rare cardiac arrhythmia disorder, causally related to SCN5A
mutations in around 20% of cases,,. Through a genome-wide association study of 312 …

Background—Aldosterone (ALD) has been shown to stimulate cardiac collagen synthesis
and fibroblast proliferation via activation of local mineralocorticoid receptors. In patients with …

BACKGROUND: The mortality and morbidity rates of various cardiovascular diseases differ
between Western countries and Japan. The age-and gender-specific prevalence rate of …

Background—Data on the Jervell and Lange-Nielsen syndrome (J-LN), the long-QT
syndrome (LQTS) variant associated with deafness and caused by homozygous or …

ATP-sensitive K+(K ATP) channels play a crucial role in coupling metabolic energy to the
membrane potential of cells. We have isolated a cDNA encoding a novel member (uK ATP …

Background—Experimental studies suggest that the interval between peak and end of T
wave (Tpe) in transmural ECGs reflects transmural dispersion of repolarization (TDR), which …

Background: In the short-to mid-term, cardiomyocytes generated from human-induced
pluripotent stem cells (hiPSC-CMs) have been reported to be less mature than those of adult …