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The association between apnoea-hypopnoea index and flow-mediated dilation of brachial artery
  1. Tomoyuki Kawada
  1. Correspondence to Professor Tomoyuki Kawada, Department of Hygiene and Public Health, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-Ku, Tokyo 113-8602, Japan; kawada{at}

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To the Editor I read with interest the cross-sectional study by Namtvedt et al 1 for 77 adults who were sampled from 30 000 individuals aged 30–65 years. They concluded that there was a significant positive association between obstructive sleep apnoea (OSA) and endothelial dysfunction by using indicators of apnoea–hypopnoea index (AHI), flow-mediated dilatation (FMD), sex and some cardiovascular risk factors. Atkinson made a query on the validity of FMD on their study,2 and I present some statistical concerns …

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  • Contributors I have read this correspondence, contributed to it and approved its submission to Heart.

  • Competing interests The author has indicated no financial support, and there is no conflict of interest in this study.

  • Provenance and peer review Not commissioned; internally peer reviewed.

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