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Coronary artery disease review series
Lessons from primary PCI practice for the next decade
  1. Leong Lee,
  2. Chetan Varma
  1. Department of Cardiology, City Hospital, Birmingham, UK
  1. Correspondence to Dr Chetan Varma, Department of Cardiology, City Hospital, Dudley Road, Birmingham B18 7QH UK; c.varma{at}


Primary percutaneous coronary intervention (PPCI) is the reperfusion treatment of choice for acute ST-elevation myocardial infarction with studies having demonstrated improved outcomes with PPCI over thrombolysis. Its use has increased substantially over the last decade, overtaking thrombolytic therapy in many countries. This has been paralleled with advances in adjunctive technology and pharmacological therapy to further improve outcome, but challenges remain for PPCI practitioners. The evidence behind PPCI is reviewed at every stage of the patient's journey.


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