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The Authors’ reply
  1. Konstantinos Toutouzas1,
  2. Maria Drakopoulou1,
  3. Constantina Aggeli1,
  4. Charalampia Nikolaou1,
  5. Ioannis Felekos1,
  6. Haralampos Grassos1,
  7. Andreas Synetos1,
  8. Konstantinos Stathogiannis1,
  9. Antonis Karanasos1,
  10. Eleftherios Tsiamis1,
  11. Elias Siores2,
  12. Christodoulos Stefanadis1
  1. 1First Department of Cardiology, Hippokration Hospital, Athens, Greece
  2. 2Centre for Materials Research & Innovation, University of Bolton, Bolton, UK
  1. Correspondence to Professor Konstantinos Toutouzas, First Department of Cardiology, Hippokration Hospital, 24 Karaoli and Dimitriou str., Holargos, Athens 15562, Greece; ktoutouz{at}

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We thank Dr Marijan Bosevski for his comments1 and appreciate his interest in our recent publication.2 In this letter, Dr Bosevski addresses an important issue concerning the potential prognostic implication of carotid plaque thermal heterogeneity or/and plaque neoangiogenesis, when added in current risk stratification models to improve the overall predictive ability for cardiovascular events. Although our study was not oriented towards prognosis, this is certainly an issue worthy of further discussion.

Since the last few years, there …

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