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To the Editor,
In a recent article of Candilio et al1 assessing the effect of remote ischaemic preconditioning (RIPC) on postoperative outcomes in patients undergoing cardiac surgery, they showed that RIPC reduced the amount of perioperative myocardial injury by 26% and the incidence of acute kidney injury by 48%. They should be applauded for trying to control most of the risk factors affecting postoperative myocardial and kidney injury. However, to differentiate the effects of one factor on study endpoints, all other factors have to be standardised. In this study, several …
Contributors FSX read the manuscript of Candilio et al.; analysed their methods and data; suggested comment points and drafted this manuscript; responsible for this manuscript; and approved the final manuscript. RPL read the paper of Candilio et al.; analysed their data; revised the comment points and this manuscript; and approved the final manuscript. XLC read the manuscript of Candilio et al.; analysed their methods and data; revised the comment points and this manuscript; and approved the final manuscript.
Competing interests None.
Provenance and peer review Not commissioned; internally peer reviewed.