Background Intensive lifestyle change programs are utilised in cardiovascular disease prevention, but their efficacy is variable. Real-time monitoring of patients is feasible.

Purpose To evaluate the efficacy of real-time adherence monitoring of patient diet and exercise, in targeting metabolic syndrome parameters of bmi, blood pressure (bp) and total cholesterol (tc), in overweight/obese (owo) individuals.

Methods 28 owo (bmi >25 and <40) persons were enrolled. At entry, 16 had elevated bp (>140/90), 12 elevated tc (>5 mmol/l). Baseline resting metabolic rate (rmr) and bmi was calculated. Participants had a reduced daily calorie intake (~300–500 kcal below rmr) and increased daily exercise (10³–12.5³ steps). Phone app training tracked caloric intake, while a wireless weighing- scale and pedometer, enabled daily weight tracking and exercise adherence monitoring. Non-adherents received motivational emails, sms or phonecall. Participants were met weekly, face to face or via video-link. The primary aim was to assess the effects on weight loss. Secondarily, bp and tc were analysed.

Results Significant weight loss was achieved at weeks 4, 8 and 12 with an average weight reduction of 5.6%, 9.6% and 10.1% (p < 0.01 for each time point). In 16 hypertensive subjects, average systolic bp declined 17.1%, and diastolic bp was 14.7%. In the raised tc cohort, average tc reduced from 6.21 mmol/l to 4.97 mmol/l or 19.94%.

Conclusion Intense lifestyle and behavioural intervention, coupled with real-time remote monitoring of patients diet, exercise and weight has a substantial positive effect on metabolic syndrome parameters and may have a seminal role to play in cardiovascular disease prevention.

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Abstract 43 Figure 1

Results