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Regarding sex differences in cardiovascular ageing: let us not forget iron
  1. Allison Merz1,
  2. Susan Cheng1,2
  1. 1Department of Cardiovascular Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA
  2. 2Framingham Heart Study, Framingham, Massachusetts, USA
  1. Correspondence to Dr Susan Cheng, Cardiovascular Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA; scheng{at}

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The Authors’ reply We thank Dr Goldstein1 for bringing to our attention the iron hypothesis as a potential non-hormonal factor contributing to sex differences in cardiovascular ageing. We also find intriguing the possibility that iron depletion in menstruating women may be cardioprotective. We had previously been aware of the potential role of iron as a by-product of haeme …

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  • Contributors AM and SC drafted the work and revised it for critical intellectual content.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

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