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Contributors Both authors made substantial contributions to the drafting of this manuscript.
Competing interests CSPL is supported by a Clinician Scientist Award from the National Medical Research Council of Singapore; has received research support from Boston Scientific, Medtronic, and Vifor Pharma; and has consulted for Bayer, Novartis, Takeda, Merck, AstraZeneca, Janssen Research & Development, LLC and Menarini. LHL is supported by a Clinical Research Award from the Swedish Research Council; has received research support from Boston Scientific, AstraZeneca, Medtronic and Thoratec and lecture and/or consulting honoraria from AstraZeneca, Novartis, Vifor Pharma, Servier, St Jude and Medtronic.
Provenance and peer review Commissioned; internally peer reviewed.